Lazio

Lazio vs Pisa Prediction — Serie A

Serie ASaturday, May 23, 2026 at 06:45 PM
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Our prediction: Lazio to win 2-0, with solid betting value on Lazio -1 Asian handicap and a lean toward Pisa not to score.

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Prediction Summary

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Match Winner

Lazio69%
Draw19%
Pisa12%

Predicted Score

2 - 0

Confidence

78%

Betting Advice

Back Lazio to win and consider Lazio -1 on the Asian handicap; Pisa to struggle in attack.

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Predicted Lineups

Match Analysis

Our prediction: Lazio to win 2-0, with solid betting value on Lazio -1 Asian handicap and a lean toward Pisa not to score.

Match preview

Lazio welcome bottom‑placed Pisa to the Stadio Olimpico in what should be a controlled home performance from Maurizio Sarri’s side. With Lazio pushing to cement a top‑half finish and Pisa already effectively condemned, this looks like a spot where quality, depth and structure should tell.

Lazio arrive off the back of a statement 2-0 derby win over Roma, while Pisa’s latest reference point away to a big side is a bruising 0-3 defeat at Napoli. The gap between ninth and twentieth in Serie A is wide on paper and even wider on the pitch right now.

Why this prediction

Our baseline call is Lazio to win 2-0. The numbers and situational factors both point toward a controlled home victory with a decent chance of a clean sheet.

Lazio’s recent record (3W-3D-4L, 11 scored, 14 conceded over 10) doesn’t scream dominance, but that form includes two meetings with Inter and some awkward fixtures. Pisa, by contrast, sit on just 18 points from 37 games, averaging 0.9 goals for and conceding 2.1 in their last ten – classic relegation‑level metrics.

When you overlay that with Pisa’s missing defensive leader and Lazio’s attacking tools in a 4-3-3, a two-goal margin for the hosts becomes the likeliest scenario.

Team analysis

Lazio under Maurizio Sarri

Sarri has stayed loyal to a 4-3-3, with Noslin and Dia giving central penetration and a rotating cast of wingers – Cancellieri, Isaksen, Zaccagni and veteran Pedro – attacking the half-spaces. The full-backs push high, especially Pellegrini on the left, while Basic, Dele-Bashiru and Cataldi share the midfield load with Rovella suspended.

At the back, Romagnoli and Mario Gila provide a solid central pairing, and Marušić remains a reliable outlet at right-back. Even with Provedel sidelined, this is a defensive unit that can control a struggling attack like Pisa’s, especially at home.

Pisa under Oscar Hiljemark

Hiljemark has set Pisa up in various versions of a back three – 3-5-2, 3-4-2-1, 3-5-1-1 – with Semper behind a defensive line led by Caracciolo and Canestrelli, plus Bozhinov or Angori. Wing-backs Léris and Angori try to provide width, while the midfield (Aebischer, Højholt, Akinsanmiro) works hard but lacks top‑tier creativity.

Up front, Moreo and Stojilković are honest, physical forwards but need service and early crosses to be effective. Against deeper, more compact defences, Pisa often run out of ideas and get forced into low‑percentage shots.

Key missing players and their impact

Lazio absences

  • Ivan Provedel (shoulder) – First-choice goalkeeper and a calming presence in build‑up. His shot‑stopping and command of the box have saved Lazio repeatedly. His absence does slightly raise the variance at the back, but Motta and Furlanetto have already shared minutes, and the defensive structure in front of them is stable.
  • Nicolò Rovella (red card) – Key in Sarri’s possession game as a deep orchestrator. Without him, Cataldi is the natural pivot, offering good passing but a bit less press resistance. It marginally lowers Lazio’s ceiling in tight games, but against Pisa’s passive press, the downgrade is manageable.
  • Nuno Tavares & K. Taylor (suspended) – Tavares’ attacking thrust from left-back is a miss; he’s aggressive and breaks lines with carries. Pellegrini is a more traditional full-back but still offers quality delivery. Taylor has provided legs and dynamism as a mezzala; Basic and Dele-Bashiru can cover his role.
  • Patric & M. Zaccagni (questionable) – Patric is mainly depth at this stage, while Zaccagni is a genuine creative outlet between the lines. If Zaccagni doesn’t start, Cancellieri or Isaksen will likely take his minutes. Lazio lose some subtlety and 1v1 quality, but still retain enough pace and movement out wide.

The key point: Lazio’s injuries and suspensions affect depth and build‑up quality more than their overall dominance level in this matchup.

Pisa absences

  • Andrea Caracciolo (suspended) – This is huge. Caracciolo is the leader of the back three, excellent in the air and responsible for organising the line. Without him, Pisa must lean on Canestrelli and the younger Bozhinov, which weakens both experience and set‑piece defence. Against a Lazio side strong on dead balls and crosses, that’s a real concern.
  • Coppola, Denoon, Lorran, Tramoni (questionable) – These are more rotation and depth pieces across midfield and attack. Limited minutes mean their possible absence primarily restricts Hiljemark’s ability to change games from the bench rather than weakening the starting XI significantly.

Caracciolo’s suspension, combined with Pisa’s already poor defensive record away, is one of the main reasons our model leans toward a multi‑goal home win.

Expected goals (xG) analysis

We can estimate xG trends from recent attacking and defensive numbers:

  • Lazio: 11 goals scored and 14 conceded in their last 10 roughly map to an xG for around 1.4–1.5 and xG against around 1.3–1.4 per game, given the quality of opposition. They often create good openings but can be a little wasteful.
  • Pisa: 9 scored and 21 conceded over 10 suggests xG for around 0.9–1.0 and xG against around 1.9–2.0 per match. That xG against figure is relegation‑level – they regularly allow high‑quality shots in central areas.

The xG differential therefore sits roughly at:

  • Lazio: +0.1 to +0.2 per game
  • Pisa: -0.9 to -1.0 per game

In a single match, that kind of gap often translates to a one to two‑goal expected margin. With Lazio at home and Pisa missing their best centre‑back, the underlying expected goals profile clearly supports a 2-0 or 3-1 type outcome.

Key stats behind the pick

  • Lazio last 10: 1.1 scored / 1.4 conceded per game, but vs stronger average opposition.
  • Pisa last 10: 0.9 scored / 2.1 conceded; heavy defensive leak.
  • Pisa bottom of the table with 18 points in 37 matches – 0.49 points per game.
  • Pisa’s recent trips to top sides: 0-3 vs Napoli, 2-1 loss vs Lecce, often conceding multiple goals.

Taken together, these point to Lazio being far more likely to win, and Pisa being more likely to fail to score than the raw BTTS odds imply.

Value bets vs 1xBet odds

1xBet prices:

  • 1X2: Lazio 1.61 | Draw 4.40 | Pisa 6.03
  • O/U 2.5: Over 1.86 | Under 2.09
  • BTTS: Yes 1.83 | No 1.89

Our probabilities:

  • Lazio win ~69% (fair odds ~1.45)
  • Draw ~19% (fair odds ~5.25)
  • Pisa win ~12% (fair odds ~8.33)

At 1.61, the market still offers a bit of value on Lazio to win, as we rate their chance noticeably higher than the implied ~62%.

We project about a 47% chance of both teams scoring, which is slightly below the 52–53% implied by BTTS Yes at 1.83. That tilts the value toward BTTS No at 1.89, in line with a 2-0 type result and Pisa’s low attacking xG.

On the goals line, we lean Over 2.5 at 56% vs odds implying about 53–54%. It’s a slim edge, but given Pisa’s tendency to concede heavily away, the over is mildly attractive, especially aligned with a Lazio‑heavy scoreline.

Asian Handicap predictions

With a predicted 2-0 Lazio win and about a 69% home‑win chance, Asian Handicap markets around Lazio -1 look interesting.

  • On Lazio -0.5 (equivalent to home win), the edge mirrors the 1X2 market – modest but positive.
  • On Lazio -1, our distribution sees a strong likelihood of a one or two‑goal victory. The most frequent exact scorelines in our model cluster are 2-0 and 2-1, followed by 3-0. That means a high probability of at least a push, with a good chance to win.
  • Going to Lazio -1.25 or -1.5 is more aggressive. It can still be justified for higher risk‑tolerant bettors, but Pisa’s capacity to park deep and scrape a 1-0 or 2-1 outcome should be respected.

The best balance of risk and value sits on Lazio -1 Asian handicap: it aligns with the projected xG margin and our 2-0 predicted scoreline, while protecting you with a push in case Lazio only win by one.

Risk & bankroll notes

No bet is risk‑free, and there are a few caveats here. Lazio’s season has been inconsistent, and without Provedel and Rovella, they lose some stability in two key areas. If they start slowly or underestimate already‑doomed Pisa, this could drift into a laboured 1-0 or 1-1.

Pisa, meanwhile, have nothing to lose and could adopt a very conservative, low‑block approach with five at the back, aiming to frustrate and steal set‑pieces. That game script reduces margin of victory and slightly caps the upside of big handicaps.

As always, stakes should be sized conservatively – even a strong edge in a single football match rarely warrants more than a small percentage of your total betting bankroll.

Frequently Asked Questions

What is the predicted score for Lazio vs Pisa in Serie A?

We project a 2-0 win for Lazio against Pisa, driven by the hosts’ superior quality, Pisa’s weak defensive numbers and the absence of Caracciolo. The tactical and xG trends both back a controlled, multi-goal home victory with a good chance of a clean sheet.

Which team is more likely to win, Lazio or Pisa?

Lazio are clear favourites, with our model giving them about a 69% chance of victory. Pisa sit last in Serie A, concede heavily away, and are missing defensive leader Caracciolo, all of which strongly favours a home win at the Stadio Olimpico.

What are the best value bets for Lazio vs Pisa?

The standout angles are Lazio to win at 1.61, Lazio -1 on the Asian handicap, and a lean toward BTTS No at 1.89. Our probabilities rate Lazio’s win chance higher than the market and see Pisa struggling to score against a solid home defence.

Will both teams score in Lazio vs Pisa?

We rate both teams to score at roughly 47%, slightly below the market. Pisa’s attack averages under a goal per game recently and faces a structured Lazio back line, so BTTS No has a small edge, fitting a 2-0 or 3-0 type scoreline.

Who are the key players to watch in Lazio vs Pisa?

For Lazio, Noslin, Dia and the wide forwards (Cancellieri, Isaksen) should trouble Pisa’s weakened back three. For Pisa, Moreo and Stojilković are the main threats, but they may be isolated without Caracciolo’s influence helping them build from the back.

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Prediction Reasoning

Our model expects Lazio to control this game and win with a reasonable degree of comfort, around a 70% chance of a home victory. Pisa’s attacking numbers are weak, and their defensive issues away from home make a clean-sheet home win a realistic base case.

Looking at recent form, Lazio’s 3W-3D-4L in the last ten is mid-table, but the context matters: they’ve just come off a morale-boosting 2-0 derby win over Roma and two losses to a far stronger Inter side. They average 1.1 goals for and 1.4 against over that period, which is modest, but the underlying level of opposition has generally been higher than what Pisa will present.

Pisa’s form line is far more fragile. Four wins and six losses in their last ten, with 0.9 goals scored and 2.1 conceded per game, paints the picture of a team that can be competitive against weaker or similar-level opponents but tends to be heavily exposed against top-half sides. The 0-3 defeat to Napoli is a good indicator of how they struggle when they’re forced back and can’t control territory.

From a tactical angle, Maurizio Sarri has kept Lazio in a 4-3-3, with Noslin, Dia, Cancellieri/Isaksen providing vertical threat. They don’t need to turn this into a shootout; controlling possession and working high-quality chances will suit them. Hiljemark’s Pisa have leaned on a back three (3-5-2/3-4-2-1), but the wing-backs often get pinned deep against stronger opponents, leaving the forwards isolated. That structure can become a 5-3-2 under pressure, which reduces their already limited attacking output.

Key absences tilt the balance further toward Lazio. They are without first-choice keeper Ivan Provedel, plus Rovella, Nuno Tavares and K. Taylor through suspension. Provedel’s absence slightly increases defensive risk, but Motta and Furlanetto have already had minutes, and the defensive block in front (Romagnoli, Gila, Marusic, Pellegrini/Provstgaard) is intact. Missing Rovella and Taylor affects midfield rotation more than the starting XI, because Basic, Cataldi and Dele-Bashiru can still give Sarri a solid three. Zaccagni and Patric being questionable is a watchpoint, but there is depth in the wide roles (Isaksen, Cancellieri, Pedro for a farewell cameo) and at the back.

For Pisa, the absence of Caracciolo through suspension is a major blow. He’s a leader in that back three and their most experienced central defender. Without him, Canestrelli and Bozhinov likely anchor the defence with Calabresi or Angori, which reduces aerial dominance and organisation. Several attacking and midfield options (Coppola, Denoon, Lorran, Tramoni) are questionable, further limiting Hiljemark’s ability to change the game from the bench if they fall behind.

Head-to-head data is thin: just one recent competitive meeting, a 0-0. It doesn’t override the broader indicators: Lazio are a solid top-half Serie A side at home, Pisa sit 20th with only 18 points after 37 games, and their goal difference and away defensive record are poor. Market odds reflect this, but our model is a bit more bullish on Lazio’s control and Pisa’s scoring difficulties.

Given Lazio’s recent performances, home advantage at the Stadio Olimpico, and Pisa’s defensive issues and missing defensive leader, a 2-0 home win aligns with the quantitative and qualitative picture. Probabilistically, we see Lazio covering a -1 line more often than not, with a moderate likelihood that Pisa fail to score at all.

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This article was generated with the help of AI models trained on football data and reviewed by our editorial staff for accuracy.

Odds accurate at time of writing and subject to change.